Two problems related to car will not start have been reported for the 2008 Buick Lucerne.
Car would not start, and the fuel relay fuse had blown, damaging the fuse box. Fuse was replaced and on Dec 4, 2013 the car would not start again. New fuse block had to be installed. Mechanic's diagnoses said the fuel pump was not receiving good voltage at time, further inspection and testing showed under the rear seal left side fuse block is receiving good voltage but sending a low voltage signal to the fuel pump. Further investigation shows a burnt and melted high resistance connection at the fuel pump relay. Normally, I understand the fuse next to the relay should have blown. Problem seems to stem with the fuse box and there was only one available in the united states on 12/4/2013 which I got. My mechanic was told they are on national backorder and it could take up to 6 months to receive one. So there is an obvious problem with these fuse boxes.
Purchased vehicle 4/2/12. 6/30/12 car would not start. Full power and crank but would not engage. Car towed and diagnosed as fuel pump/relay. The relay was melted. Repaired without incident. July 23,2012 car repeated. No start. Car towed again and relay is melted again. Researching it seems to be a common event occurring in 2008 v8. Mechanic has determined it to be an electrical problem stemming from fuse and amps being delivered to relay.