One problem related to engine noise has been reported for the 2001 Acura MDX. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2001 Acura MDX based on all problems reported for the 2001 MDX.
Motor mounts going bad and breaking in Mdx Acura 01-current. Replacing between 40k-80k. Intake system clogged (airport) gives bad gas mileage and to unclogg runs $200 at dealership. Makes vibration and noise as if you are going over a speed bump heading towards a toll booth.