One problem related to wiring has been reported for the 2001 Buick Lesabre. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2001 Buick Lesabre based on all problems reported for the 2001 Lesabre.
Operating mechanisms on the rear window broke causing the window to go down and stay down. We had to replace the whole mechanism. A few months later the other rear window did the same thing. I think the cables are defective. Is there a recall on the mechanisms? we also had to replace an idler pulley after 40,000 miles.