One problem related to engine clicking and tapping noises has been reported for the 2001 Buick Regal. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2001 Buick Regal based on all problems reported for the 2001 Regal.
At about 80,000 miles grinding noise in right front wheel developed, replaced brakes and rotors found the right front wheel bearing was bad and had to have it replaced . At about 84,000 miles the lifters were making a ticking noise that sounded like a helicopter, replaced the lifters at a cost of $1600 this was just one month after the final payment of the 5 year loan one month after the lifters were replaced the engine seized up needed to be towed and I'm told that the main bearing has gone bad and the engine needs to be replaced or rebuilt.