One problem related to transmission failure has been reported for the 2001 Chrysler 300M. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2001 Chrysler 300M based on all problems reported for the 2001 300M.
There was no initial warning previous to malfunction. Traveling down I-64 in norfolk, va transmission failed at 63,000 miles. Transmission needed to be replaced. Estimated $3,800 in damage. Failure could have easily caused a catastrophic accident.