One problem related to manual transmission column shift has been reported for the 2006 Dodge Ram 2500. The most recently reported issues are listed below.
Column shifter lever had been difficult to move for months from p (park) to any other gear (r, d, 1-2-3). The shifting mechanism broke today after I started the engine (truck had been parked overnight in my home's driveway) when I tried to move the shifter from park to reverse to exit the driveway and drive vehicle elsewhere. Shifter will not engage transmission into any gear now; truck is not drivable. Required an oversize rollback tow truck to come get it and take it to a repair shop since my pickup has a long bed.