One problem related to driveshaft has been reported for the 2008 Dodge Ram 2500. The most recently reported issues are listed below.
Vehicle has a vibration starting at 50 mph that appears to be due to a drive component. Diagnosed and replaced the drive shaft rear u-joint. Some play also found in the left front u-joint (4wd) that was replaced 8 months ago. This is the third time in 4 years that u-joints had to be replaced on this vehicle.