One problem related to defogger has been reported for the 2006 Ford E-350. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2006 Ford E-350 based on all problems reported for the 2006 E-350.
The contact owns a 2006 Ford E-350. The contact stated that while driving 60 mph, the rear air conditioning unit failed to blow out cool air. The vehicle was taken to the dealer for diagnosis but they were unable to duplicate the problem. The vehicle was not repaired and the manufacturer was not notified. The approximate failure mileage was 120,000.