One problem related to brakes failed has been reported for the 2013 Ford F-450. The most recently reported issues are listed below.
I64 westbound sandstone mountain w va 8 mile 6% grade realized integrated trailer brakes failed and had 2 use manual brake option on brake control. Was never given any warning by truck that trailer brake controller had failed. I am experienced enough to know how to manually operate trailer brakes from the controller. Inexperienced operators may not be so fortunate.