One problem related to air brake wheel speed sensor has been reported for the 2000 GMC C2500. The most recently reported issues are listed below.
While driving the wheels do not spin at a uniform speed which causes the vehicle to spin out of control, one one occasion while driving in icy conditions consumer tried different transmission setting but the vehicle continued to slide across the road, a missing wheel speed sensor was installed but that did not resolve the problem with the uneven acceleration and swerving. Nlm.