One problem related to driveshaft has been reported for the 2001 GMC C2500. The most recently reported issues are listed below.
While shifting from park to drive a clicking noise was heard coming from underneath the vehicle. While driving,the driver experiencing a fluctuate in speed. This cause the vehicle to accelerated intermittently. The driver was able to drive the vehicle to the dealer for inspection. The mechanic informed the driver front and rear u joints needed replacing from the drive shaft.