One problem related to transmission failure has been reported for the 2000 GMC Savana. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2000 GMC Savana based on all problems reported for the 2000 Savana.
Automatic transmission failure. Repair shop stated a bearing failed causing transmission to fail.
| Transmission Failure problems | |
| Axle Assembly problems | |
| Transmission Not Engage problems |