One problem related to axle assembly has been reported for the 2001 GMC Sierra 1500. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2001 GMC Sierra 1500 based on all problems reported for the 2001 Sierra 1500.
The vehicle experienced rear axle problems.
| Power Train problems | |
| Transmission Gear Slipping problems | |
| Axle Assembly problems |