One problem related to air conditioner has been reported for the 2006 GMC Sierra 1500. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2006 GMC Sierra 1500 based on all problems reported for the 2006 Sierra 1500.
Air conditioner fan resistor failed filling pickup cab with smoke. Was repaired under warranty and failed again, burning part of the wiring harness.
| Equipment problems | |
| Radio/tape Cd Player problems | |
| Air Conditioner problems | |
| Carrier/rack problems |