One problem related to engine failure has been reported for the 2012 Honda Odyssey. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2012 Honda Odyssey based on all problems reported for the 2012 Odyssey.
1. Brakes and rotors are undersized and warped causing a massive vibration when you break. Honda dealers worked 3 times on it but the problem continued until I purchased after market parts and replaced them. 2. I received no warranty letter or warning about an engine failure (piston recall warning) letting me know that the engine needed repairs. I was on a trip when the car almost stalled on the freeway and I had to take evasive actions to prevent a devastating accident.