One problem related to check engine light on has been reported for the 2006 Honda Pilot. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2006 Honda Pilot based on all problems reported for the 2006 Pilot.
My 2006 Honda Pilot started to show the p0301 error code and had the check engine light and vtm-4 caution light come on suddenly. Both lights came on when I pulled out of my driveway on a Monday morning. The day before I had driven my car about 20 miles on an interstate highway and about 2 miles on city roads. The lights were not on at that time nor were any obstacles hit, such as potholes, and no change in the driving characteristics of the car were experienced. I took the car to a local repair shop which diagnosed the problem as a misfire in the number one cylinder caused by faulty valves. I have since taken it to a shop which reconditions and repairs engines as a specialty. They found the same problem and also found that the intake snorkel was split in two. Looking online it appears there was a recall for 2009 to 2012 Honda Pilots which experienced similar failures which Honda USA settled. I am concerned a similar fault happened in my 2006 Honda Pilot and would like the NHTSA to investigate based on Honda's settlement.