One problem related to engine has been reported for the 2001 Jeep Cherokee. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2001 Jeep Cherokee based on all problems reported for the 2001 Cherokee.
2001 Jeep Cherokee 128,000 miles has a cracked cylinder head between ports #3 and #4. This seems to be a common flaw on 00-01 Jeeps with the cylinder head cast # 0331.