One problem related to windshield has been reported for the 2007 Lexus IS250. The most recently reported issues are listed below.
I have a 2007 Lexus is 250. I've had it for 7 years now and love everything about it. But about 2-3 years ago, the vinyl interior starting getting sticky. It's gotten worse that if you touch it the color comes off on your fingers. I have a big shiny area on the dashboard which reflects on the front windshield and makes visibility difficult. I know there's others here in south florida with the same issue, that have gone to Lexus and have been told they have to pay to replace it, that it's not covered.