One problem related to engine failure has been reported for the 1999 Lexus RX300. The most recently reported issues are listed below.
Engine failed due to sludge. Took to arbitration did not win. Vehicle out of service for last 10 months. Lexus dealer and customer service contacted over 50 times. Even with new policy engine still has not been repaired. Lexus and dealer have treated me like a villian. Piad for vehicle that is unuseable.