One problem related to engine has been reported for the 2000 Lexus RX300. The most recently reported issues are listed below.
Traveling 60 mph on merit pky connecticut, the fluid leaked out of a blown gasket in the transfer box to the rear wheel drive. The rear wheels locked up and car skidded 150 ft and spun. A miracle no cars or barriers were hit. Mother suffered nerve damage from being twisted. Had car towed directly to dealer. The dealer - Lexus of englewood NJ, made an attempt to pay off lease and lease a new car but did not follow through with their offer. They treated us horribly!!! they gave us no information on what happened to the truck and through a mired of lies and nasty phone calls from them, we have decided to buy a mercedes ml350. I will never drive a Lexus again and am currently proceeding with litigation against Lexus and Lexus of englewood NJ. I've searched the internet for similar problems but found none. This incident, I believe was an original defect or caused by the incompetence of the service department of Lexus of englewood. The service manager john lomando has deceived, lied and been down right nasty to us. The truck was serviced on time every service with Lexus of englewood.