One problem related to automatic transmission park/neutral start switch has been reported for the 2001 Lexus RX300. The most recently reported issues are listed below.
Vehicle was at a full stop and put into park. Pavement was level. Parking brake was not engaged. Both driver side doors were open and rear door lifted. I was loading vehicle for full 5 minutes. As I turned, saw vehicle begin to move in reverse at a very fast pace. Rolled into exterior stucco wall of garage. Damaged bumper and lift gate. No injuries. When the vehicle is put into park while running, when auto is put in reverse and foot is taken off brake the vehicle moves backward very quickly with no gas applied. When put in forward, it creeps at a slower speed than reverse. There is absolutely no possibility that the vehicle was left in reverse when the accident occured. The car would have knocked me over before I could have cleared it because it moves so fast in reverse.