One problem related to tailgate has been reported for the 2008 Lexus RX350. The most recently reported issues are listed below.
Rubber on tailgate handle melted. I believe this is due to an electrical problem. I went online and found many other similar complaints. This may be a fire hazard. Now the tailgate goes up, and then automatically comes right down. The first time it happened the heavy tailgate hit me on the top of my head causing a great deal of pain and some bleeding. I have read that the same thing has happened to others. This is very dangerous. It does not always happen. It tends to happen when the weather is cooler out.