One problem related to fuel hoses lines/piping and fittings has been reported for the 2005 Mercedes Benz E350. The most recently reported issues are listed below.
The contact owns a 2005 Mercedes Benz E350. The contact noticed the check engine light illuminating along with a leak underneath her vehicle. The vehicle was then inspected by a dealer who advised her that when the fuel level was low and she added fuel outside air was entering the tank causing the leak. The entire fuel line and tank were repaired. The manufacturer was contacted and advised her that they would not offer any assistance. The VIN was unavailable.