One problem related to software has been reported for the 2006 Mercedes Benz E350. The most recently reported issues are listed below.
The contact owns a 2006 Mercedes Benz E350. The contact stated that the vehicle failed to start. The vehicle was towed to the dealer. The technician diagnosed that the software calibration number needed to be recoded. The vehicle was repaired. The manufacturer was notified of the failure. The failure mileage was 92,934.