One problem related to blind spot detection has been reported for the 2012 Mercedes Benz E350. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2012 Mercedes Benz E350 based on all problems reported for the 2012 E350.
Rear sub frame corroded which results in unsafe driving, corroded brake line which results in unsafe driving. Blind spot sensor in the bumper is corroded due to no protection against environment.