One problem related to tire sidewall has been reported for the 2005 Mercedes Benz E500. The most recently reported issues are listed below.
Consumer bought this new vehicle in July of 2004, in feburary 2005 hit a slight bump and experienced a flat tire. Since then , had 3 more flats tires from very minor ridges in the road. Spoke with the manufacturer who offered to replace one tire with org type tires, spoken with manufacturer again, and they offered to replace 2 tires with contipro contact tires, as long as he bought 2 tires at retail.