One problem related to adaptive cruise control has been reported for the 2011 Mercedes Benz E550. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2011 Mercedes Benz E550 based on all problems reported for the 2011 E550.
When I parked my car there was a loud hissing sound near left front end but no smoke or anything from under the hood. When I drove it again I received a warning of (malfunction) when I was turning left the front left tire was grinding on the actual car and barely made it home. The car warning turned red and said pull over car too low. When I parked the car the front left side is now sitting on tire and touching the ground. Unable to drive. Not been investigated by a mechanic, insurance, etc. There was also an airbag warning before this issue.