One problem related to engine failure has been reported for the 2000 Mercedes Benz E Class. The most recently reported issues are listed below.
: the contact stated while driving 65 mph on the highway, there was a loss of all vehicle power, and the engine stalled without warning. The contact maneuvered the vehicle to the side of the road. The engine would not restart. The vehicle was towed to the dealer, who determined the me control module of the engine failed and needed to be replaced. The manufacturer was alerted.