One problem related to transmission gear slipping has been reported for the 2000 Mercedes Benz S430. The most recently reported issues are listed below.
On 11/18/16 I was driving my 2000 S430 when wile accelerating to merge onto the freeway my transmission slipped causing my engine to rev. I released the gas pedal & tried to press it again to re engage the transmission but it didn't work. I pulled to the side of the road, placed the car in park, then back to drive. I cautiously drove back home & parked the car until I was able to get a shop appointment. On 11/21/16 I took the car to the shop, they said the fluid was full but the transmission was slipping & needed to be replaced? so I took it home to think, (no problems while driving home). On 11/22/16 I drove the car out of town & after about 20 miles my cluster gauge started flickering then went out. However, the blinkers still worked along with the hazards. So when I was done with my appointment I checked my fuses & replaced the ones indicated on the chart. While a small portion of the lights came back on it was briefly & then everything went out, blinkers & all. So in all my frustration, I've parked the car & am attempting to get help. I found there were recalls on the gauges but not my VIN? is this somehow connected to my transmission? please help.