One problem related to wiring has been reported for the 2006 Mini Cooper S. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2006 Mini Cooper S based on all problems reported for the 2006 Cooper S.
Traveling on highway at 70mph and instrument panel lights up, speeds drops to maximum 30mph creating unsafe driving condition. First occurrence March 2012 was diagnosed as failed "throttle body", second occurrence in July 2012 was diagnosed as failed "wiring harness".