110 problems have been reported for the 1999 Nissan Altima. The following chart shows the 20 most common problems for 1999 Nissan Altima. The number one most common problem is related to the vehicle's service brakes, hydraulic with 18 problems. The second most common problem is related to the vehicle's air bags (13 problems).
The following chart shows the number of problems reported during each of the service years since the debut of the 1999 Nissan Altima in 1999.
| Service Year | Number of Problems |
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| 2022 | |
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| 1999 |
When making the decision between buying a new or used Nissan Altima, the following table can be used to compare the 1999 Nissan Altima with the Nissan Altima from other model years. Note that the number of problems reported for the 1999 Altima is 110 while the average number of problems reported for the 26 model years of the Nissan Altima is 651.