One problem related to ignition switch has been reported for the 2006 Nissan Titan. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2006 Nissan Titan based on all problems reported for the 2006 Titan.
On 05/22/2015, traveling on interstate highway at or near posted speed in mild sunny weather. The truck just shut off in lane of traffic. There was no hesitation, noise, alarm, warning lights just shut down. There was no power steering or power brakes. Pulled vehicle over to rh shoulder and tried to restart it with out success. On 05/18/2015, I had the truck serviced and inspected at a Nissan dealership in anticipation of this road trip. The truck passed dealer inspection. I had the truck towed to a Nissan dealer service center and after several days the dealer told me the ecm had failed and shorted out the ignition switch. The repair bill was a little over $1400. I am not objecting to the cost of repair. . . . I am concerned about the truck just stopping on the highway without warning. If this breakdown would have happened in the middle or driving lanes of a nearby freeway, or on a steep incline with turns the results may have been very bad. The dealership said the short and failure of the ecm were a result of a leak in the exhaust system (same one that passed inspection) and heat shorted the wiring harness. I feel the wiring harness may be too close to the heat of the exhaust system and could have been isolated as not to cause failure. Updated 8/31/cn.