One problem related to brakes failed has been reported for the 2000 Toyota 4Runner. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2000 Toyota 4Runner based on all problems reported for the 2000 4Runner.
Toyota recommends in the owners manual that brakes be inspected each 7500 miles. I did not see this in my manual. This is the only notice an owner receives. At 19,900 miles my rear brakes failed because adjustments had not been made every 7500 miles. I did not get any warning lights, only rear brake failure. If the general maintenance is not performed each 7500 miles the brakes can fail and mine did. The manufacturer will not cover this under the warranty. There is no warning before rear brake failure. The owner must rely on their memory to ensure safe operation of rear brakes.