One problem related to brake disc caliper has been reported for the 2006 Toyota Avalon. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2006 Toyota Avalon based on all problems reported for the 2006 Avalon.
Right front caliper froze; did not retract piston. No braking as a result of brake pads destroyed. . After repair in 2012, same caliper again froze and required identical repair in April of 2015 at 58,000 miles.