One problem related to differential unit has been reported for the 2000 Toyota Camry. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2000 Toyota Camry based on all problems reported for the 2000 Camry.
On June 12, 2010, my Toyota Camry (yr 2000, 4 cyl, ce) made a strange sound from the engine at 60-70 mph on an interstate highway. After another 30 min of strange sound coming out from the engine, the engine below started to make loud cranking sound. I pulled in to the service road of the highway and after a few more cranking sound, the car was completely disabled. I called the police to get it towed to a nearby town. On June 14, I arranged to have the car towed back to my hometown 120 miles away. The Toyota dealer inspected the car and said that the differential part of the transmission was totally damaged. The service person said that it is out of ordinary for a car of this type and mileage to have transmission breakdown. I have kept the car under regular maintenance ever since I bought the car in 1999. This transmission breakdown occurred at 72,000 miles and the transmission was serviced for a leak at 66,000 mile at the same Toyota dealer. I suspect my Toyota Camry had pre-existing manufacturing defects in the transmission that caused this catastrophic transmission breakdown problem. It happened when I was driving on a highway. Called the Toyota company and filed a complaint. Toyota said that my car is out of warranty.