One problem related to o2 sensor has been reported for the 2016 Toyota Prius. The most recently reported issues are listed below.
I have owned several Toyota vehicles over the years - a tercel, a rav4, a tacoma and a Prius v. Recently I was hit with a $1680 + repair to my 2016 Prius v due to �rodent damage� to my wiring. This included damage to 3 out 4 brake lines, an O2 sensor line, a fuel line sensor and possibly a fuel pump wiring harness. The check engine light came on while driving at 60mph. I was driving on 1 working brake line!! my car was in the Toyota shop for 3 days. I've read that Toyota denies responsibility for using wiring that attracts rodent chewing. I have been forced to take this loss of use and damage to my auto insurance policy and am extremely concerned that I will face this type of damage in the future with more catastrophic results like an accident. This possibility makes the ownership of a my Prius financially and practically untenable!!! I can't depend on my Prius to be able to drive me to my work or and any other destination safely if the design of this vehicle makes the wiring accessible to rodents. I can't kill every rodent that may encounter my car in every location I park or drive my car!! since this has happened not only to me but also other Toyota owners, I want to know what Toyota is doing to prevent and/or correct this problem? I'm having to pay for installing new wiring, which unless the Toyota service center doing the repair does something to prevent this from happening again, the wiring will still be subject to the same destruction due to Toyota's bad design and/or inferior materials that permit rodent damage.