Two problems related to battery dead have been reported for the 2016 Acura MDX. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2016 Acura MDX based on all problems reported for the 2016 MDX.
Car electrical activated when start button was pushed but it wasn't clear if engine was running. Car would not "turn off" or lock. Many error messages came across dash and car was not properly recognizing fobs. An Acura service center was called and we were told our only option was to disconnect battery leads or let the car run until the battery died. Many hours later the battery died. When the Acura service truck came to get us they couldn't even get the car into neutral after charging the battery and wheel truck had to be called. The dealership had the car for weeks and was not able to determine the pause. We have multiple videos of the incident. Note that the car was not in accessory mode and the behavior is inconsistent with accessory mode.
Inexplainable battery drain on several occasions resulting in not enough power to start car. No solution from Acura except that it happens to a lot of owners. Most recently car died in an intersection (with two kids in car) and could not restart or shift to neutral (without power) to move out of intersection. Car was stopped at intersection, driver moved forward to make turn, driver stopped in intersection and auto-idle engaged (turning car off momentarily), when driver released brake, which would normally restart engine, car would not restart due to loss of power. Stuck for an hour in middle of intersection until jumped. Three days prior to that, car sat for 5 days without use in 40-50 degree weather, and battery was dead when attempted to start. Seems to be a parasitic drain or faulty charging electrical problem with car.