One problem related to transmission failure has been reported for the 2016 Acura MDX. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2016 Acura MDX based on all problems reported for the 2016 MDX.
Three times while travelling on the interstate my vehicle suddenly shifted into second gear while I was trying to accelerate, and got stuck there. It suddenly dropped my speed from 70 mph to 30. I was presented with several alerts on my dash (emissions failure, sh-awd failure, transmission failure). I was able to continue driving at 30 mph until I could get to a safe area. After I turned off the vehicle and waited for a period of time the warnings would clear. I was finally able to get the vehicle to a dealership while the warnings were present. I was told after diagnosis that the transmission software needed to be updated. After the update the problem has not presented itself again. I was told software updates are not covered under warranty unless they are a recall issue.