One problem related to ignition switch has been reported for the 2010 Chrysler 300. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2010 Chrysler 300 based on all problems reported for the 2010 300.
Ignition switch caused engine to shut down while driving and caused problems with starting. After three trips to dealer problem was found to be the ignition switch and was replaced. Stalling while driving is a safety issue that should be cause for a recall. Note! the expensive ignition switch was replaced at my cost. I have the repair invoices.