One problem related to software has been reported for the 1999 Dodge Ram 2500. The most recently reported issues are listed below.
Before any engine performance up grade, recognized after tbs 18-019-01 installed in the ecm/pcm of my 1999 Dodge diesel 2500 24v coolant not circulating through engine. Temp fix with new ecm and TSB upgrade 10-040-02. No code or serious over heat especially during winter months. But does run 190 degrees or more up hill- winter months. Scalding signs inside engine at thermostat change. Mechanic clueless upon visual over pressure of top radiator hose after engine reaches operating temps. Software seem to go into default or hacked cal mode. With this decrease in performance is suddenly mileage decrease, power and shifting erratic suddenly. Other symptoms not obvious either. Again everything seem fine after last software boot but after 100 miles or so returning home from out of town dealership, truck running loosely after over night sit.