One problem related to transmission failure has been reported for the 2000 Dodge Ram 2500. The most recently reported issues are listed below.
No notice of a problem, did all manufacturers required oil changes, transmission failed at 63,000 miles. Manufacturer, daimler Chrysler refused to repair, transmission replacement found special optional trans oil cooler failed which cause trans failure. Had to replace all items at a cost of 4000. 00.