One problem related to engine has been reported for the 1999 Ford E-150. The most recently reported issues are listed below.
The spark plug blew out on my Ford e150. This is a ridiculously common problem with Ford trucks/vans/ suvs- why is Ford allowed to get away with this? just google "Ford spar" and instantly "Ford spark plug blowout" pops up- there are hundreds of webpages about this, yet Ford continues to escape liability for their poor design. Can't someone make these people @ Ford do the right thing and fix it?.