One problem related to suspension has been reported for the 1999 Ford E-350. The most recently reported issues are listed below.
Vehicle sways and bottoms out. Box on the truck falls down and hits the tires. It is 1500lbs under gross weight. Contacted dealer, they had called the region engineer. Vehicle does not meet gvw standards.
| Suspension Noise problems | |
| Front Suspension problems | |
| Suspension problems |