One problem related to brake electric antilock has been reported for the 2000 Ford E-350. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2000 Ford E-350 based on all problems reported for the 2000 E-350.
When braking on patchy areas, consumer states that the stopping distance is terrible and longer than the stopping distance of other vehicles.
| Service Brakes problems | |
| Brake Disc Rotor problems | |
| Brake Disc Pads problems | |
| Brake Electric Antilock problems |