One problem related to alternator/generator/regulator has been reported for the 2006 Ford E-450. The most recently reported issues are listed below.
Fire ignited at engine compartment wiring harness to alternator resulting in replacement of alternator, alternator wiring harness, right glow plug wiring harness, engine compartment wiring harness and fire damaged hoses and belts.
| Electrical System problems | |
| Battery problems | |
| Alternator/generator/regulator problems |