One problem related to power train driveline has been reported for the 2008 Ford F-150. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2008 Ford F-150 based on all problems reported for the 2008 F-150.
The vehicle started a vibration and loud banging noise. Unable to drive. Looking under vehicle found center support/carrier bearing out of place and laying in bracket that attaches it to frame. Could not drive over 5-10 mph. Had vehicle towed to dealer garage. Complete drive shaft(s) assembly was replaced. Old parts were retained by garage.