One problem related to tank filler pipe and cap has been reported for the 2001 GMC Sierra. The most recently reported issues are listed below.
While driving and with no warning, the vehicle leaked fuel. Dealer notified. Injector pump failed, truck would run but fuel would run down the side of the engine with it running on the exhaust pipe, possible fire condition.
| Fuel Pump problems | |
| Gasoline Fuel System problems | |
| Fuel Injection problems | |
| Tank Filler Pipe And Cap problems | |
| Fuel Delivery problems |