One problem related to engine shut off without warning has been reported for the 2001 Honda Odyssey. The most recently reported issues are listed below. Please also check out the statistics and reliability analysis of the 2001 Honda Odyssey based on all problems reported for the 2001 Odyssey.
I was driving in motion in a neighborhood and the engine cut off and could barely pull over cause the steering locked up. Before that, I was leaving a gas station and again the engine shut off while in motion.