One problem related to passenger side frontal has been reported for the 2010 Lexus IS250. The most recently reported issues are listed below.
Lexus consumer writes in regards to vehicle airbag explosion during accident. The consumer stated his wife was a passenger in the vehicle which rear ended another vehicle. The consumer's wife stated the explosion of the air bag and flying debris caused more injuries than the accident itself.
| Air Bag problems | |
| Front Driver Side Air Bag Inflator problems | |
| Air Bag Not Deploy problems | |
| Passenger Side Frontal problems | |
| Air Bag Light On problems |