One problem related to radio/tape cd player has been reported for the 2008 Lexus LS460. The most recently reported issues are listed below.
Sudden, loud, high-pitched, repetitive, chirping noise while my wife was driving on a freeway. She was frightened and felt forced to take her eyes off the road to check the instrument panel. She nearly struck another car. The problem turned out to be due to a failed radio amplifier. The loud noise had persisted even with the radio off.
| Equipment problems | |
| Carrier/rack problems | |
| Radio/tape Cd Player problems | |
| Navigational (global Positioning System) Gps problems | |
| Air Conditioner problems |